10 Best Hand Sanitizers Reviews & Buyer’s Guide for 2022

Hand sanitizers exist for a very long, but let’s say that in 2020 they took a disproportionate place in our lives. And it’s true that some hand sanitizers are really better than others.

Best Hand Sanitizer

The hygiene of the hands is really important for good health and undoubtedly the best option is using hand sanitizer. Anyone at least once in a modern human lifetime has purchased a hand Disinfectant. However, all hand sanitizers don’t work well on germs and bacteria. Some of these contain harsh chemicals and have serious health consequences for you and your loved ones.

If you are looking for the best hand sanitizer, you are in the right place. Here we present a selection of the best quality hand disinfectants that are analyzed by our expert medical team. We have put together detailed information with the pros and cons of each model we have reviewed.

Our recommendation is based on tons of hour’s research, test, data aggregated from different sources and expertise support. For example, consumer association test reports, WTO (World Health Organization), field reports, and real customer reviews.

Best Hand Sanitizers in 2022

As we previously mentioned, some of these products may contain aggressive chemicals that are seriously dangerous for human health. But don’t despair! In our guide, you will find many of them completely safe for our health while performing excellently the germicidal function.

However, the best hand sanitizer on the market is undoubtedly PURELL. It comes in several sizes, ranging from a mini bottle for the handbag (which costs just a few dollars) to a liter container with a pump.

10 Best Hand Sanitizers – At a Glance

  • 1. Purell Advanced Hand Sanitizer
  • 2. Purell Gell Hand Sanitizer Table Top Pump Bottle
  • 3. CleanWell Botanical Antibacterial Foaming For Home Gym
  • 4. Five Star-Star San – High Foaming Sanitizer
  • 5. Clorox 02176 Hand Sanitizer with Spray
  • 6. Germ-X Hand Sanitizer
  • 7. Purell Advanced Hand Sanitizer
  • 8. Purell Travel Sized Hand Sanitizer
  • 9. Germ-X Hand Sanitizer, Aloe
  • 10. Babyganics Alcohol-Free Hand Sanitizer

1. Purell 8 fl oz pump bottle Advanced Hand Sanitizer

Purell Advanced

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Purell is the best quality hand sanitizer brand on the market as it leaves hands clean without leaving any odor whatsoever. It is a good feeling to have this product on hand and a sense of security at any time. This can be used to refill a 1-oz purse or travel-sized container. It is gentler on the skin than the plain ones.

Purell hand sanitizer is enhanced with four nourishing skin-conditioning agents in a skin-friendly formulation that’s mild on hands. It is clinically proven and effective to maintain skin health, skin moisture and skin feel.

This advanced hand sanitizer itself just seems so much more smooth and not dry on your hands! And, the dispenser itself is very handy and smooth. You can remove the cap from several travel bottles and pump the gel into them.

However, it takes a little time and patience to work the air out as you fill. This decorative Purell hand sanitizer is also perfect for in-home use in kitchens, bathrooms, mudrooms or diaper changing areas.

It has Aloe in it which is great for kids’ skin. Its gel formulation with emollient products makes it ideal even for those who have very delicate skin. Overall, these are great to carry around the house to keep germs at bay, especially when it’s cold and flu season.


  • Great size for unlike other brands
  • It doesn’t dry out your hands too terribly
  • Perfect for multi-purpose use such as travel, home, gym, office, and more
  • Extremely effective against bacteria
  • Fine for sensitive skin
  • Evaporates quickly


  • This product is not gluten-free

2. PURELL Advanced Hand Sanitizer & Refreshing Gel

Refreshing Gel

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We need to mention that PURELL Hand Sanitizer was invented in 1988 by Gojo to meet the needs of healthcare providers and restaurant operators looking for ways to reduce the spread of germs. But now they produce different sizes of bottles for different people’s needs and budgets.

It kills the most germs: just one squirt of the Purell Advanced Hand Sanitizer kills as many germs as 2 squirts of any other national brand. That’s why you will find more options from the PURELL in this list.

This advanced hand sanitizer works great for viruses and looks pretty good. The bottles are prettier than the usual hand sanitizer bottles. It is convenient when you don’t have a bathroom in your dorm room and want to clean your hands quickly. Because the size is appropriate for sitting on a tabletop in any room.

This 8 fl oz pump bottle model is enhanced with four nourishing skin-conditioning agents. It’s a step up above the usual if you are going to have it sitting somewhere prominent.

However, the advanced design means the bottle is unstable. Instead of a broad bottom, which would make sense, they have “designed” it by cutting along the edges at an angle, destroying the stability of the bottles. If you do not set them down carefully, they will fall over.


  • Bottles look pretty nice
  • It keeps 99.9 percent germ-free
  • Comes with safely packaged
  • Perfect size for any room
  • Designed for frequent use


  • Very pungent alcohol smell

3. CleanWell Botanical Antibacterial Nontoxic Hand Sanitizer

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There are so many great things about the CleanWell sanitizer: It lasts for a long time because of the foaming pump. And you may know that a foaming disinfectant is the best choice when you have children in your home. No nasty chemicals and your hands feel clean after using it instead of grubby like traditional sanitizer.

CleanWell Botanical hand sanitizer is also good for those with sensitive skin. It smells great and I recommend it for anyone with a baby or who gets dry hands easily.

It is Kids-Friendly and made with only plant-based ingredients – no animal products, no harsh ingredients, and no toxic chemicals. The price is cheap (costs close to the same as this size) compared to buying several individual bottles, and it means less plastic waste.

The active ingredient in CleanWell products is Thymol, a component of thyme oil. Thymol has been clinically proven to kill over 99.9% of common household germs, specifically Influenza A, Rhinovirus, Staphylococcus Aureus, Salmonella Enterica, Pseudomonas Aeruginosa, and Escherichia coli.

It is a particularly practical sanitizing gel to be used in any situation where you want to clean or sanitize your hands. In a few seconds, your hands will be sanitized and fragrant.


  • Nontoxic and smell pretty strong
  • Kid-safe and great for soft-skin
  • Very reasonable price
  • Certified cruelty-free
  • Fresh clean scent


  • It can’t be refilled
  • Small capacity

4. Five Star 6022b_ – Star San High Foaming Sanitizer

High Foaming Sanitizer

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If you are looking for an ideal food-safe sanitizer that can use for both home and commercial use, then the Five Star is the best option for you. This single bottle provides approximately 150 gallons of sanitizing fluid, ideal for home brewing, small restaurants, and any other situation where you do not want bacteria but don’t want to smell or taste cleaner. It works as a germicide to you eliminate 99.9% of the germs.

All products have been formulated to work on every type of brewing equipment, while also maintaining the integrity of the surface. If making high-quality beer, wine, cider, or spirits is your priority, the Five Star sanitizer should be your first choice for all of your cleaning and sanitizing needs.

However, this container is specifically designed for use in industries such as food processing and manufacturing so it would be ideal for that. As with sanitizing anything, you will want to first clean the surface with an appropriate cleanser and then sanitize it with Star San.

Five Star sanitizer contains a fair amount of phosphoric acid, and if this is combined with calcium, then you’ll get calcium phosphate, which is not soluble in water. Be careful with storing long term. It seems to need to vent a bit and will leak if left closed for a long time, and as it’s an acid, it’ll do damage to whatever it leaks on.


  • Reduces water spotting
  • Versatile use
  • Safe for use on most brewing equipment surfaces
  • Short contact time
  • No rinse necessary
  • Self-foaming


  • Foam is somewhat intimidating

5. Clorox (02176) Hand Sanitizer with Moisturizer

Clorox Hand Sanitizer

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The Clorox is a wonderful hand sanitizer for sensitive skin! It is liquid and evaporates quickly and does not have much of an odor. The best thing about it, though, is that the alcohol content is high enough that it will kill norovirus, the most common cause of gastroenteritis, which most other hand sanitizers (especially the gel type) do not.

It’s not a stream of liquid or a gel. It has a wide fine mist to it and does an outstanding job of coating the hands. This bottle is perfect for having in an office, for keeping in the cup holder of the car, etc. It doesn’t leave that horrible alcohol film. It is an extremely effective product against viruses and bacteria.

There are no perfumes to linger and spoil the smell and taste of food, and although the product says it has some skin moisturizers, they don’t dwell on your hands. It takes a few times of getting used to the feel of it when you squirt it into your hands, as everyone is used to the gel type.

Clorox hand disinfectant can be used on any occasion when there is not an immediate availability of soap and water to clean the hands. The product is contained in a 16.9oz bottle and represents. In our opinion, it is the best solution to the relationship between quality and price.


  • Bleach-free formula kills 99.999% of germs in 15 seconds
  • Provides broad-spectrum antimicrobial activity
  • It doesn’t dry your hands out too bad
  • From Clorox Commercial Solutions
  • Very cheap price


  • It can be a little harsh on your hands

6. Germ-X Hand Sanitizer with Convenient Pump Bottle

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The Germ-X is a perfect six-packs hand sanitizer at a reasonable cost. Each bottle is 30 ounces, and the 6 of them add up to 180 ounces. This is a great product and not sticky.

Germ-x hand sanitizer smells good and leaves hands soft. The formula of63 percent ethyl alcohol makes it an excellent antiseptic that has a drying effect so that the gel will dry quickly. It is an ecological and biodegradable sanitizer that will ensure a soft touch on your hands.

It has a moisturizing formula that leaves your hands feeling clean and refreshed after using it. Germ-X hand sanitizer kills 99.99% of many common harmful germs and bacteria in as little as 15 seconds. Aloe formula with Vitamin E makes it gentle enough for hands and faces (even the little ones).

It has a convenient pump for easy dispensing. The skin-friendly aloe formula that’s mild on the hands leaving hands feeling soft and fresh. Germ X with aloe is green and has aloe vera that not only keeps the hands soft but also from cracking.

It has an aloe vera scent too, very mild smell, and is an extremely effective product against bacteria.


  • Kills germs and bacteria less than 15 seconds
  • Aloe formula with Vitamin E
  • Skin-friendly aloe formula
  • Convenient 8-ounce size
  • Reasonable price


  • Ethyl Alcohol only 62% (antiseptic)

7. Purell Travel Size 125pcs Advanced Hand Sanitizer

Travel Size Hand Sanitizer

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When you eat in a restaurant, the menu you are holding in your hands was last held by a snotty-nosed kid who coughed and sneezed all over it. Then you are holding that menu in your hand, right before you pick up the food to eat it. Use the Purell single-pack hand sanitizer after you are done with the menu.

PURELL travel-size advanced hand sanitizer is manufactured with a 3-year expiration. The specific expiration date is visible on the individual packets. It is made of 70% ethyl alcohol. Having these little packets makes it somewhat easier to be more discreet about using hand sanitizer in the company of others.

These single-pack hand sanitizers are perfect for all professionals use and daily consumers and healthcare professionals who administer home health care. Also great for people who want on-the-go cleaning and refreshing for Travel, Exercise, and Outdoor Sporting Events and Concerts.

The package comes with 125 pieces. The amount of liquid is enough to cleanse both hands thoroughly. These things are pretty handy, especially if you’re sharing with someone who wants some of your sanitizers.

You don’t have to worry about sharing one of those pocket-sized bottles with anyone and making sure you don’t accidentally leave it on the restaurant table like I’ve done so many times before.


  • Smell exactly like regular Purell 1 liter bottles
  • 125 individual packets in a display box
  • You can put it in a pocket to have handy
  • One-handed operation
  • Great choice for everyone


  • Sometimes you forget where you put it (size fact)

8. Germ-X 30oz Pump Bottle 4-Pack Hand Sanitizer

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This is the small package of the Germ-X hand sanitizer, each bottle is 30 ounces, the 4 of them add up to 120 ounces. It is a great antiseptic that has a fast-drying effect so that the gel will dry very quickly. The liquid is not sticky. Germ-x hand sanitizer also smells good and leaves hands soft.

It contains aloe vera that not only keeps the hands soft but also from cracking. It has an aloe vera scent too, a very mild smell. Germ-X hand cleaner is cruelty-free, therefore not tested on animals. This is an excellent product if you are in the Germ prevention frame of mind and a great value for the money, especially compared to other more expensive brands.

Like all the Germ X hand sanitizers, this product is formulated to meet FDA standards for humans. Therefore, you should talk to your vet about effective hand cleaners to use before handling tropical birds. This moisturizing hand sanitizer works well on both viruses and Bacteria.

Wet hands thoroughly with product and allow to dry without wiping; for children under 6, use only under adult supervision; not recommended for infants.


  • Moisturizing with Vitamin E
  • Fits on any desk, counter or sink
  • Perfect for the car door side pocket and the diaper bag
  • They don’t dry out your hands
  • Each bottle is 30 ounces


  • The pump won’t get the last half inch out well

9. Babyganics Alcohol-Free Pump Foaming Hand Sanitizer

Foaming Hand Sanitizer

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Your whole family is diving into babyhood hands, especially the baby’s sensitive skin with Babyganics hand hygiene line. These Alcohol-Free Hand Sanitizers are designed with little ones in mind because it contains low levels of cleansing agents that are perfect for use on little hands.

This does not make your hands sticky at all. You won’t get the alcohol cooling feeling when using this product and it takes a bit longer to rub in (by a few seconds), but the big plus side is that your hands don’t dry out with multiple uses per day and you aren’t overwhelmed since there is no scent.

The pump is also easy to use, but the product is a little watery. A little goes a long way, so little hands might have a tendency to pump too much at once.

A small size 8.45oz bottle makes them easily transportable and they are very easy to find in your bag! The pump bottle is small enough to put in your diaper bag without a push handle to avoid a mess. Overall, Babyganics is an amazing product for a healthy life and I would encourage you to try it out.


  • Plant-derived ingredients
  • It is completely Alcohol-free
  • Healthy moisturizing formula
  • Non-allergenic – dermatologist tested
  • Best quality hand sanitizer ever


  • Smell that is hardly noticeable unless you hold your hands to your nose

10. Purell Travel Sized Flip Cap Bottles with Display Bowl

Travel Sized Flip Cap Bottles

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They are the 1 oz mini travel size in a large plastic bowl. For example, the one you see hanging outside of some women’s purses. The expiration date is on the bottle and the case.

Like most Purell hand sanitizers, it kills 99.99% of the most common germs that may cause illness and viruses would be included. It is ethyl alcohol, which is an antimicrobial substance.

It is a clinically tested hydroalcoholic product and is gentle on the skin. Resealable tape seals the label in quarter fold onto the back of each bottle and allows the label to be opened wide from the back and refolded and re-taped to the back again.

This Display Bowl hand sanitizer could be a substantial gift for those parents and grandparents (and yourself) who whip these out before eating out or at home or camping.

You are getting a lot of these little bottles by buying them in this package, but the expiration date is three years from now, so you should be able to use them up in that time even if you are not sharing them with the family.


  • Good for ease-of-access
  • Handy to keep one everywhere you spend time
  • Comes in a nice package
  • Very convenient container
  • Great choice for smart travelers


  • Active Ingredient 62% Ethyl Alcohol
  • Only one-ounce size bottles

Bonus Review:

#SheaMoisture Antibacterial Hand Sanitizer for Dry Skin

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The SheaMoisture Advanced Original Hand Sanitizer kills more than 99.99% of many common germs and bacteria from our hands. It has a mild, fresh scent. This is a cheap alternative that can just be placed on tables and bathroom counters around the building.

Compared to its competitors and the most widely advertised hand sanitizer on the market, this advanced gel is suitable for those who don’t like too strong smells. The view you are looking at is four – each bottle contains 8 oz and a total of 32oz. This item is also available in different sizes.

It isn’t a substitute for hand washing but if you can’t wash your hands, this is an excellent alternative. The SheaMoisture is every bit as good as Purell or any of the other premium brands. It is a great alternative to name-brand products. The scent is a tad strong but great for sensitive skin.

However, this is a home consumer product; anything with a downward-oriented dispensing pump needs a counter or table. It is a truly excellent product at a reasonable cost, thanks to its light fragrance.


  • Perfect cleanser for dry skin
  • Dries quickly without leaving a smell
  • Leaves hands feeling soft
  • Advanced formula
  • The smell is really good


  • Small size

Tips for Choosing the Best Hand Sanitizers

If you are considering acquiring a high-quality hand sanitizer, you have to know several points to avoid the risk of skin problems. There are currently different brands producing high-quality hand sanitizer because of the COVID-19 Pandemic. But not all brands work well on this type of virus. That is why when selecting the hand disinfectant, consider some important features that we’re going to discuss below.

Quality of the hand sanitizers

First, a quality hand sanitizer should always help you eliminate bacteria and prevent infections at the time when you can not wash your hands because you do not have water or soap nearby. It is a good idea if we are away from home and we are going to eat or if we have to do some work that requires good hygiene.

Quality Hand sanitizers have the following characteristics:

  • They smell good, or at least they don’t smell too chemical or yucky
  • Have a pleasant texture – neither too “oily” nor sticky
  • Absorb quickly into the skin
  • Don’t make hands dry and can even help moisturize them.

Antiseptic formula

Keep in mind that the hand sanitizer you choose has an alcohol content with a concentration greater than sixty percent. Otherwise, the sanitizer won’t act efficiently to kill the germs completely. If you prefer to select a hand sanitizer that does not contain alcohol very well or less than 60%, it could be very harmful to health, and cause various problems such as weakness in the muscles or even allergies.

In some hand sanitizers, instead of alcohol, we find other substances such as disinfectant additives or antibacterial chemicals that effectively kill bacteria.

However, we do not recommend hand sanitizers that include triclosan or benzalkonium.

Healthy & safety

You should remember that these are strong products and therefore you should keep them out of the reach of children because they can suffer intoxication. When children need to clean their hands with sanitizer, they always do it under adult supervision and if possible the best thing is that they do not use these products constantly because young skins are more sensitive to all kinds of exposure.

We recommend that you always select hand sanitizers that are as natural as possible. It is not necessary that they smell good because normally if they do it is because they will have many more chemicals, so it is always a better option to choose more natural products.

The price

The price varies depending on the product and its composition. A cheaper product is not as effective as one at a higher price. Before buying a hand sanitizer at a cheap price, you must be careful that there are no harmful substances inside, such as synthetic fragrances and additives that are dangerous to health.

Our advice is therefore to buy products that are effective in sanitizing, and disinfecting, and are also safe for your health. You don’t need to worry about the excessive price because it can vary from 2 to 5 dollars.

Frequently Asked Questions

How to use hand sanitizer?

The way and time you use hand sanitizer affect its effectiveness. If used on visibly dirty hands, many hand sanitizers will not have a beneficial effect on the germs that settle there. If applied instead on fairly clean hands, you leave it on for thirty seconds, taking care to let it dry, and you will have the maximum antiseptic action.

Hand sanitizer can not only kill bacteria but also some fungi and viruses and is more effective in preventing infections or bacterial diseases if you use it only when it is really needed and in moderation.

Well-recognized hygiene organizations, even World Health Organization (WTO) recommend to use hand sanitizer only if soap and water are not available.

When do the hands need to be disinfected?

  • When entering the production rooms or the work area.
  • When actively handling food.
  • After working with critical food such as meat, poultry, fish and eggs.
  • After cleaning work or working with rubbish and dirt
  • After using the toilet or, and this is very important, blowing your nose.
  • Before putting on work shoes or boots and after taking them off.
  • Before putting on disposable gloves and after removing them.

Does the hand sanitizer really work?

We say yes, but its effectiveness depends on what you want to achieve and on its use. As we already mentioned, the places where the sanitizer can come back really useful are those where it is essential to wash your hands and where germs are more prone to nest as hospitals or nursery schools.

Many studies have shown that the presence and use of hand sanitizers in schools would help children protect themselves from the spread of infections and viruses and therefore would be useful to prevent children from becoming sick and absent from school. The same goes for the workplace.

Which elements a good hand sanitizer must have?

A good hand sanitizer must contain at least 60% alcohol, otherwise it cannot guarantee the elimination of viruses and bacteria. It must contain emollient products to avoid causing damage to the skin. It must be contained in convenient and handy dispensers so that it can store in the bag and always have them at hand. Because alcohol-free hand sanitizer can cause troubling side effects and therefore pose a potential health hazard.


The best option to clean hands is always water and soap but hand disinfectants are a very effective alternative to use eventually in some specific cases. Therefore, when selecting a hand sanitizer, you should always review its composition in order to choose the best high-quality products that can help you disinfect your hands to be very efficient and keep yourself hydrated and healthy at all times and in any place.

Are you ready to pick the one that is suitable for your budget? We hope that this article has managed to address you in the best possible way to choose an effective hand sanitizer.

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Liam Dean is a Professional Blogger and Outdoor Enthusiast. He completed Masters in Sports Sciences and spend all of his free time doing sports and other outdoor activities. During vacations, he goes hunting, fishing and mountaineering.

1 thought on “10 Best Hand Sanitizers Reviews & Buyer’s Guide for 2022”

  1. can I order some my employees hands are cracking and need something that will sooth their hands. I just bought gloves but wont be here for a while. I’m a pizza parlor trying to keep up with demand and protect my employees as much as possible. We are overwhelmed with orders and that just tells you how much they are cleaning their hands. If you have any suggestions ill be more than happy to take them. I am out of ideas. Been I think everywhere but most are saved for hospitals. I am next going to
    the PX to see what I can get there.


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