10 Best Hand Sanitizers Reviews & Buyer’s Guide for 2022

The sanitizers exist for very long, but let’s say that in 2020 they took a disproportionate place in our lives. And it’s true that some hand sanitizers are really better than others.

Best Hand Sanitizer

The hygiene of the hands is really important for good health, undoubtedly the best option is hand sanitizer. Anyone, at least once in their lifetime, has purchased a hand sanitizer. Here we present a selection of the best quality hand disinfectants that are analyzed by our experts. We also have put together detailed information with pros and cons.

Our recommendation is based on data aggregated from different sources. For example, consumer association test reports, field reports, and real customer reviews.

Best Hand Sanitizers in 2022

As previously mentioned, hand sanitizers are not all the same. Some of these products may contain aggressive chemicals that are seriously dangerous for human health. But don’t despair! In our ranking, you will find many of them completely safe for your health while performing excellently the germicidal function.

However, the best hand sanitizer on the market undoubtedly PURELL. It comes in several sizes, ranging from a mini bottle for the handbag (which costs just a few dollars) to a liter container with a pump.

10 Best Hand Sanitizers – At a Glance

  1. Purell Advanced Hand Sanitizer
  2. Purell Gell Hand Sanitizer Table Top Pump Bottle
  3. CleanWell Botanical Antibacterial Foaming For Home Gym
  4. Five Star-Star San – High Foaming Sanitizer
  5. Clorox 02176 Hand Sanitizer with Spray
  6. Germ-X Hand Sanitizer
  7. Purell Advanced Hand Sanitizer
  8. Purell Travel Sized Hand Sanitizer
  9. Germ-X Hand Sanitizer, Aloe
  10. Babyganics Alcohol-Free Hand Sanitizer

1. Purell Advanced Hand Sanitizer – 8 fl oz pump bottle

Purell Advanced

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Purell is the best quality hand sanitizer on the market as it leaves hands clean without leaving any odor what so ever. It is a good feeling to have this product on hand and a sense of security at any time. This can be used to refill a 1-oz purse or travel-sized container. It is gentler on the skin than the plain ones.

Purell hand sanitizer enhanced with four nourishing skin-conditioning agents in a skin-friendly formulation that’s mild on hands. It is clinically proven and effective to maintain skin health, skin moisture and skin feel. The hand sanitizer itself just seems so much more smooth and not drying on your hands! And, the dispenser itself is very handy and smooth.

You can remove the cap from several travel bottles and pumped the gel into them. It takes a little time and patience to work the air out as you fill. This decorative Purell hand sanitizer is also perfect for in-home use in kitchens, bathrooms, mudrooms or diaper changing areas.

These are great to keep around the house to keep germs at bay, especially when it’s cold and flu season. This also has Aloe in it which is great for kids’ skin. Its gel formulation with emollient products makes it ideal even for those who have very delicate skin.

Why I Like It
  • Great size unlike other brands
  • It doesn’t dry out your hands too terribly
  • Perfect for multi-purpose use (travel, home, gym, office, and more)
  • Fine for sensitive skin
  • Evaporates quickly
Why I Don't Like It
  • This product is not gluten-free

2. PURELL Advanced Hand Sanitizer – Refreshing Gel

Refreshing Gel

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We need to mention, PURELL Hand Sanitizer was invented in 1988 by Gojo to meet the needs of healthcare providers and restaurant operators looking for ways to reduce the spread of germs. But now they produce different sizes of hand sanitizers for different needs.

It kills the most germs: just one squirt of best Purell Advanced Hand Sanitizer kills as many germs as 2 squirts of any other national brand. That’s why you will find more option from PURELL in this list.

The hand sanitizer also works great for virus and looks pretty. The bottles are prettier than the usual hand sanitizer bottles. It is convenient for when you don’t have a bathroom in your dorm room and want to quickly clean your hands. Because the size is appropriate for sitting on a tabletop in any room.

This 8 fl oz pump bottle hand sanitizer also enhanced with four nourishing skin-conditioning agents. It’s a step up above the usual if you are going to have it sitting somewhere prominent.

Advanced design means the bottle is unstable. Instead of a broad bottom, which would make sense, they have “designed” it by cutting along the edges at an angle, destroying the stability of the bottles. If you do not set them down carefully, they will fall over.
Why I Like It
  • The bottles look surprisingly nice
  • It keeps 99.9 percent germ-free
  • Comes with safely packaged
  • Perfect size for any room
  • Designed for frequent use
Why I Don't Like It
  • Very pungent alcohol smell

3. CleanWell Botanical Antibacterial Nontoxic Hand Sanitizer

CleanWell Kids-Friendly Hand Sanitizer

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There are so many great things about CleanWell sanitizer: It lasts for a long time because of the foaming pump. No nasty chemicals. Your hands feel clean after using it instead of grubby like traditional sanitizer. CleanWell is also good for those with sensitive skin. It smells is great and I recommend for anyone with a baby or who gets dry hands easily.

CleanWell Botanical is a Kids-Friendly Hand Sanitizer made with only plant-based ingredients – no animal products, no harsh ingredients, no toxic chemicals. The price is also cheap compared to buying several individual bottles, and it means less plastic waste. These are great considering a small bottle costs close to the same as this size. 

The active ingredient in CleanWell products is Thymol, a component of thyme oil. You may know that Thymol has been clinically proven to kill over 99.9% of common household germs, specifically Influenza A, Rhinovirus, Staphylococcus Aureus, Salmonella Enterica, Pseudomonas Aeruginosa, and Escherichia coli.

It is a particularly practical sanitizing gel to be used in any situation where you want to clean or sanitize your hands. In a few seconds, your hands will be sanitized and fragrant.

Why I Like It
  • Nontoxic and smell pretty strong
  • Kid-safe and great for soft-skin
  • Very reasonable price
  • Certified cruelty-free
  • Fresh clean scent
Why I Don't Like It
  • It can’t be refilled
  • Small capacity

4. Five Star-Star San – 32oz High Foaming Sanitizer for Commercial Use

High Foaming Sanitizer

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If you are looking for an ideal food-safe sanitizer, this is the only one. This single bottle provides approximately 150 gallons of sanitizing fluid, ideal for home brewing, small restaurants, and any other situation where you do not want bacteria but don’t want to smell or taste cleaner. It also works as a germicide to you eliminate 99.9% of the germs.

All products have been formulated to work on every type of brewing equipment, while also maintaining the integrity of the surface. If making high-quality beer, wine, cider, or spirits is your priority, we hope Five Star Chemicals should be your first choice for all of your cleaning and sanitizing needs.

Keep in mind, this container is specifically designed for use in industries such as food processing and manufacturing so it would be ideal for that. As with sanitizing anything, you will want to first clean the surface with an appropriate cleanser and then sanitize it with Star San.

The sanitizer contains a fair amount of phosphoric acid, and if this is combined with calcium, then you’ll get calcium phosphate, which is not soluble in water. Be careful with storing long term. It seems to need to vent a bit and will leak if left closed for a long time, and as it’s an acid, it’ll do damage to whatever it leaks on.
Why I Like It
  • Reduces water spotting
  • Safe for use on most brewing equipment surfaces
  • Short contact time
  • No rinse necessary
  • Self-foaming
Why I Don't Like It
  • Foam is somewhat intimidating

5. Clorox (02176) Hand Sanitizer with Moisturizer

Clorox Hand Sanitizer

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Clorox is a wonderful hand sanitizer! It is liquid and evaporates quickly, and does not have much of an odor. The best thing about it, though, is that the alcohol content is high enough that it will kill norovirus, the most common cause of gastroenteritis, which most other hand sanitizers (especially the gel type) do not.

It’s not a stream of liquid or a gel. It has a wide fine mist to it and does an outstanding job of coating the hands. This is perfect for having in an office, for keeping in the cup holder of the car, etc. It doesn’t leave that horrible alcohol film. It is an extremely effective product against viruses and bacteria.

There are no perfumes to linger and spoil the smell and taste of food, and although the product says it has some skin moisturizers, they don’t dwell on your hands. It takes a few times of getting used to the feel of it when you squirt it into your hands, as everyone is used to the gel type.

Clorox hand disinfectant can be used on any occasion when there is not an immediate availability of soap and water to clean the hands. The product is contained in a 16.9oz bottle and represents. In our opinion, this is the best solution to the relationship between quality and price.

Why I Like It
  • Bleach-free formula kills 99.999% of germs in 15 seconds
  • Provides broad-spectrum antimicrobial activity
  • It doesn’t dry your hands out too bad
  • From Clorox Commercial Solutions
  • Very cheap price
Why I Don't Like It
  • It can be a little harsh on your hands

6. Germ-X Hand Sanitizer – Aloe, Convenient Pump Bottle

Aloe Pump Bottle

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Each bottle is 30 ounces, the 6 of them add up to 180 ounces. This is a great product and not sticky. Germ-x hand sanitizer also smells good and leaves hands soft. The formula is 63 percent ethyl alcohol. This is an antiseptic that has a drying effect so that the gel will dry quickly. It is an ecological and biodegradable sanitizer that will ensure a soft touch on your hands.

This germ-killing fan favorite has a moisturizing formula that leaves your hands feeling clean and refreshed. It kills 99.99% of many common harmful germs and bacteria in as little as 15 seconds. Aloe formula with Vitamin E making it gentle enough for hands and faces (even the little ones).

It has convenient pump for easy dispensing. Skin-friendly aloe formula that’s mild on the hands leaving hands feeling soft and fresh. Germ X with aloe is green and has the aloe vera that not only keeps the hands soft but also from cracking. It has an aloe vera scent too, very mild smell, and an extremely effective product against bacteria.

Why I Like It
  • Kills germs and bacteria less than 15 seconds
  • Aloe formula with Vitamin E
  • Skin-friendly aloe formula
  • Convenient 8-ounce size
  • Reasonable price
Why I Don't Like It
  • Ethyl Alcohol only 62% (antiseptic)

7. Purell Advanced Hand Sanitizer – Travel Size

Travel Size Hand Sanitizer

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When you eat in a restaurant, keep in mind that the menu you are holding in your hands was last held by a snotty-nosed kid who coughed and sneezed all over it. Then you are holding that menu in your hand, right before you pick up the food to eat it. Use the Purell hand sanitizer after you are done with the menu.

PURELL Advanced Hand Sanitizer Gel Singles are manufactured with a 3-year expiration. The specific expiration date is visible on the individual packets. It is made of 70% ethyl alcohol. Having these little packets makes it somewhat easier to be more discreet about using hand sanitizer in the company of others.

This single pack hand sanitizers are perfect for all professionals use and daily consumers and healthcare professionals who administer home health care. Also great for people who want on-the-go cleaning and refreshing for Travel, Exercise, and Outdoor Sporting Events and Concerts.

The amount of liquid is perfect to cleanse both hands thoroughly.

These things are also pretty handy, especially if you’re sharing with someone who wants some of your sanitizers. You don’t have to worry about sharing one of those pocket-sized bottles with anyone and making sure you don’t accidentally leave it on the restaurant table like I’ve done so many times before.
Why I Like It
  • Smell exactly like regular Purell 1 liter bottles
  • 125 individual packets in a display box
  • You can put in a pocket to have handy
  • One-handed operation
  • Great choice for everyone
Why I Don't Like It
  • Sometimes you forget where you put it (size fact)

8. Germ-X 30 oz Bottle Hand Sanitizer – Aloe, Pump Bottle

Germ-X Hand Sanitizer

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This is the small package of Germ X, each bottle is 30 ounces, the 4 of them add up to 120 ounces. This is a great antiseptic that has a fast-drying effect so that the gel will dry very quickly. It is not sticky. Germ-x smells good and leaves hands soft. This is the most gentle and moisturizing hand sanitizer on the market. This cleaner is also cruelty-free, therefore not tested on animals.

It contains aloe vera that not only keeps the hands soft but also from cracking. It has an aloe vera scent too, very mild smell. This is an excellent product if you are in the Germ prevention frame of mind. And it’s a great value for the money, especially compared to other more expensive brands.

Like all Germ X hand sanitizer, this product is formulated to meet FDA standards for humans. Therefore, you should talk to your vet about effective hand cleaners to use before handling tropical birds.

Wet hands thoroughly with product and allow to dry without wiping; for children under 6, use only under adult supervision; not recommended for infants.
Why I Like It
  • Moisturizing with Vitamin E
  • Fits on any desk, counter or sink
  • Perfect for the car door side pocket and the diaper bag
  • They don’t dry out your hands
  • Each bottle is 30 ounces
Why I Don't Like It
  • Pump won’t get last half inch out well

9. Babyganics Alcohol-Free Foaming Hand Sanitizer

Foaming Hand Sanitizer

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Your whole family is diving into babyhood hands especially baby’s sensitive skin with Babyganics hand hygiene line. These Alcohol-Free Hand Sanitizers designed with little ones in mind because it contains low levels of cleansing agents that are perfect for use on little hands.

This does not make your hands sticky at all. You won’t get the alcohol cooling feeling when using this product and it takes a bit longer to rub in (by a few seconds), but the big plus side is that your hands don’t dry out with multiple uses per day and you aren’t overwhelmed since there is no scent.

The pump is easy to use, but the product is a little watery. A little goes a long way, so little hands might have a tendency to pump too much at once.

A small size of 8.45oz makes them easily transportable and they are very easy to find in your bag! It is also small enough to put in your diaper bag without a push handle to avoid a mess. Overall, it’s an amazing product and I would encourage you to try it out.

Why I Like It
  • Plant-derived ingredients
  • It is completely Alcohol-free
  • Healthy moisturizing formula
  • Non-allergenic – dermatologist tested
  • Best quality hand sanitizer ever
Why I Don't Like It
  • Smell that is hardly noticeable unless you hold your hands to your nose

10. Travel Sized Flip Cap Bottles with Display Bowl

Travel Sized Flip Cap Bottles

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They are the 1 oz mini travel size. For example, the one you see hanging outside of some women’s purses. The expiration date is on the bottle and the case. It kills 99.99% of most common germs that may cause illness and viruses would be included. It is ethyl alcohol, which is an antimicrobial substance.

These are one-ounce plastic bottles in a large plastic bowl. Resealable tape seals the label in quarter fold onto the back of each bottle and allows the label to be opened wide from the back and refolded and retaped to the back again. This could be a substantial gift for those parents and grandparents (and yourself) who whip these out before eating out or home or camping.

You are getting a lot of these little bottles by buying them in this package, but the expiration date is three years from now, so you should be able to use them up in that time even if you are not sharing them with the family. It is a clinically tested hydroalcoholic product and gentle on the skin.

Why I Like It
  • Good for ease-of-access
  • Handy to keep one everywhere you spend time
  • Comes in a nice package
  • Very convenient container
  • Great choice for smart travelers
Why I Don't Like It
  • Active Ingredient 62% Ethyl Alcohol
  • Only one-ounce size bottles

Bonus Review:

#Mountain Falls Advanced Hand Sanitizer

Mountain Falls Advanced Hand Sanitizer

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The Mountain Falls Advanced Original Hand Sanitizer kills more than 99.99% of many common germs and bacteria. Mountain Falls Hand Sanitizer has a mild, fresh scent. This is a cheap alternative that can just be placed on tables and bathroom counters around the building.

The view you are looking at is four – 32oz bottles. This item is also available in six – 8oz bottles or two – 67.6oz bottles. It is a truly excellent product and thanks to its light fragrance.

This hand sanitizer isn’t a substitute for hand washing, but if you can’t wash your hands, this is an excellent alternative. This product is every bit as good as Purell or any of the other premium brands. It is also a great alternative to the name brand products. The scent is a tad strong but great for sensitive skin.

Compared to its competitors and the most widely advertised hand sanitizer, it is also suitable for those who do not like too strong smells. This is a home consumer product, and anything with a downward oriented dispensing pump needs a counter or table. We also recommend it because of its cheap price tag.

Why I Like It
  • Combined with Vitamin E formula
  • Leaves hands feeling soft
  • Advanced formula
  • Mild alcohol scent
  • Dries quickly without leaving a smell
Why I Don't Like It
  • The scent is a tad strong

Tips For Choosing The Best Hand Sanitizers:

If you are considering acquiring a high-quality hand sanitizer, you have to know several points to avoid risky skin problem. There are currently different brands producing hand sanitizer because of the COVID-19 Pandemic. That is why when selecting the hand disinfectant, keep in mind some important features.

Quality of hand sanitizers

First, a quality hand sanitizer should always help you eliminate bacteria and prevent infections at the time, when you can not wash your hands because you do not have water or soap. It is a good idea if we are away from home and we are going to eat or if we have to do some work that requires good hygiene.

Quality Hand sanitizers have the following characteristics:

  • They smell good, or at least they don’t smell too chemical or yucky
  • Have a pleasant texture – neither too “oily” nor sticky
  • Absorb quickly into the skin
  • Don’t make hands dry and can even help moisturize them.

Antiseptic formula

Keep in mind that the hand sanitizer you choose has an alcohol content with a concentration greater than sixty percent. Otherwise, the sanitizer will not act efficiently and will not kill the germs. If you prefer to select a hand sanitizer that does not contain alcohol very well, it could be very harmful to health, and cause various problems such as weakness in the muscles or even allergies.

We do not recommend hand sanitizers that include triclosan or benzalkonium.

Healthy & safe

You should also remember these are strong products and therefore you should keep them out of the reach of children because they can suffer intoxication. When children have to clean their hands with sanitizer, they always do it under adult supervision and if possible the best thing is that they do not use these products constantly because their young skins are more sensitive to all kinds of exposure.

We also recommend that you always select hand sanitizers that are as natural as possible. It is not necessary that they smell good because normally if they do it is because they will have many more chemicals, and it is always a better option to opt for more natural products.

The price

The price varies depending on the product and its composition. A cheaper product is not as effective as one at a higher price. Before buying a product at a cheap price, you must be careful that there are no harmful substances inside, such as synthetic fragrances and additives that are dangerous to health.

Our advice is therefore to buy products that are effective in sanitizing, disinfecting and are also safe for your health. You don’t need to worry about the excessive price because it can vary from 2 to 5 dollars.

Frequently Asked Questions

How to use the hand sanitizer?

The way and time you use hand sanitizer affect its effectiveness. If used on visibly dirty hands, many hand sanitizers will not have a beneficial effect on the germs that settle there. If applied instead on fairly clean hands, you leave it on for thirty seconds, taking care to let it dry, you will have the maximum antiseptic action.

The hand sanitizer can not only kill bacteria but also some fungi and viruses and is more effective in preventing infections or bacterial diseases if you use it only when it is really needed and in moderation.

Well recognized hygiene organizations, even World Health Organization (WTO) recommend to use hand sanitizer only if soap and water are not available.

When do the hands need to be disinfected?

  • When entering the production rooms or the work area.
  • When actively handling food
  • After working with critical food such as: meat, poultry, fish and eggs.
  • After cleaning work or working with rubbish and dirt
  • After using the toilet or, and this is very important, blowing your nose.
  • Before putting on work shoes or boots and after taking them off.
  • Before putting on disposable gloves and after removing them.

Does the hand sanitizer really work?

We say yes, but its effectiveness also depends on what you want to achieve and on its use. As we already mentioned, the places where the sanitizer can come back really useful are those where it is essential to wash your hands and where germs are more prone to nest as hospitals or nursery schools.

Numerous studies have shown that the presence and use of hand sanitizers in schools would help children protect themselves from the spread of infections and viruses and therefore would be useful to prevent children from becoming sick and absent from school. The same goes for the workplace.

Which elements a good hand sanitizer must have?

A good hand sanitizer must contain at least 60% alcohol, otherwise it cannot guarantee the elimination of viruses and bacteria. It must contain emollient products to avoid causing damage to the skin. It must also be contained in convenient and handy dispensers so that it can be stored in the bag and always have them at hand.


The best option to clean hands is always water and soap but hand disinfectants are a very efficient alternative to use eventually in some specific cases. Therefore, when selecting a hand sanitizer, you should always review its composition in order to choose the best high-quality products that can help you disinfect your hands to be very efficient and keep yourself hydrated and healthy at all times and any place.

Liam Dean is a Professional Blogger and Outdoor Enthusiast. He completed masters in Sports Sciences and spend all of his free time doing sports and other outdoor activities. In vacations he go hunting, fishing and mountaineering.

1 thought on “10 Best Hand Sanitizers Reviews & Buyer’s Guide for 2022”

  1. can I order some my employees hands are cracking and need something that will sooth their hands. I just bought gloves but wont be here for a while. I’m a pizza parlor trying to keep up with demand and protect my employees as much as possible. We are overwhelmed with orders and that just tells you how much they are cleaning their hands. If you have any suggestions ill be more than happy to take them. I am out of ideas. Been I think everywhere but most are saved for hospitals. I am next going to
    the PX to see what I can get there.


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